Search results for "Oral food challenge"

showing 3 items of 3 documents

Fecal assays detect hypersensitivity to cow's milk protein and gluten in adults with irritable bowel syndrome.

2011

Background & Aims Some patients with irritable bowel syndrome (IBS)-like symptoms suffer from food hypersensitivity (FH); their symptoms improve when they are placed on elimination diets. No assays identify patients with FH with satisfactory levels of sensitivity. We determined the frequency of FH among patients with symptoms of IBS and the ability of fecal assays for tryptase, eosinophil cationic protein (ECP), or calprotectin to diagnose FH. Methods The study included 160 patients with IBS, 40 patients with other gastrointestinal diseases, and 50 healthy individuals (controls). At the start of the study, patients completed a symptom severity questionnaire, fecal samples were assayed, and …

AdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaFecal Calprotectin.AdolescentGlutensTryptaseWheat HypersensitivityGastroenterologyIrritable Bowel SyndromePlacebosFecesYoung Adultfluids and secretionsDouble-Blind MethodInternal medicineElimination dietmedicineHumansIrritable bowel syndromeFeceschemistry.chemical_classificationEosinophil cationic proteinHepatologybiologybusiness.industryOral food challengeEosinophil Cationic ProteinGastroenterologyMiddle Agedmedicine.diseaseGlutenDietchemistryGluten SensitivityImmunologybiology.proteinFemaleTryptasesCalprotectinCow’s Milk Protein HypersensitivityMilk HypersensitivitybusinessLeukocyte L1 Antigen ComplexCow’s Milk Protein Hypersensitivity; Gluten Sensitivity; Fecal Tryptase; Fecal Eosinophil Cationic Protein; Fecal Calprotectin.Fecal TryptaseFecal Eosinophil Cationic ProteinClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs? A systematic review

2015

The diagnosis of IgE-mediated egg allergy lies both on a compatible clinical history and on the results of skin prick tests (SPTs) and IgEs levels. Both tests have good sensitivity but low specificity. For this reason, oral food challenge (OFC) is the ultimate gold standard for the diagnosis. The aim of this study was to systematically review the literature in order to identify, analyze, and synthesize the predictive value of SPT and specific IgEs both to egg white and to main egg allergens and to review the cutoffs suggested in the literature. A total of 37 articles were included in this systematic review. Studies were grouped according to the degree of cooking of the egg used for OFC, age…

cut-offmedicine.medical_specialtyAllergyAdolescentImmunologyspecific IgEEgg proteinEgg Proteins Dietarymedicine.disease_causeAllergenEgg Whiteoral food challengePredictive Value of TestsRaw FoodsImmunology and AllergyMedicineHumansSerologic TestsCookingChildEgg Hypersensitivitybusiness.industryOral food challengeAge FactorsInfantGold standard (test)Immunoglobulin EIntradermal Testsmedicine.diseaseDermatologyskin prick testPredictive value of testsEgg allergyChild PreschoolPediatrics Perinatology and Child HealthImmunologyeggcut-off; egg; oral food challenge; skin prick test; specific IgEbusinessBiomarkersEgg white
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Food allergy in gastroenterologic diseases: Review of literature

2007

Food allergy is a common and increasing problem worldwide. The newly-found knowledge might provide novel experimental strategies, especially for laboratory diagnosis. Approximately 20% of the population alters their diet for a perceived adverse reaction to food, but the application of double-blind placebo-controlled oral food challenge, the “gold standard” for diagnosis of food allergy, shows that questionnaire-based studies overestimate the prevalence of food allergies. The clinical disorders determined by adverse reactions to food can be classified on the basis of immunologic or nonimmunologic mechanisms and the organ system or systems affected. Diagnosis of food allergy is based on clini…

medicine.medical_specialtyAllergySettore MED/09 - Medicina InternaEpinephrineGastrointestinal DiseasesFood allergy; gastroenterologic diseasesPopulationReviewImmunoglobulin EOral allergy syndromeFood allergyFood allergymedicineHumansAdverse effecteducationAnaphylaxisgastroenterologic diseasesSkin Testseducation.field_of_studybiologybusiness.industryOral food challengedigestive oral and skin physiologyGastroenterologyGeneral MedicineImmunoglobulin Emedicine.diseaseDermatologyImmunologyHistamine H1 Antagonistsbiology.proteinImmunotherapybusinessFood HypersensitivityAnaphylaxis
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